Why the study?
Does adherence to aspirin improve the prevention of myocardial infarction in US male physicians without prior cardiovascular disease?
Does adherence to aspirin improve the prevention of myocardial infarction in US male physicians without prior cardiovascular disease?
Excellent adherence to aspirin in primary prevention is associated with a significant reduction in myocardial infarction, whereas poor adherence yields smaller, non-significant benefits.
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Excellent adherence to aspirin may substantially lower MI risk in primary prevention; extends RCT evidence by identifying adherence as a key effect modifier.
Robert J. Glynn (1994) studied this question.
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