Why the study?
Does prior antiplatelet use affect recanalization rate and outcome in acute ischemic stroke patients receiving IV rt-PA?
Population
284 acute ischemic stroke patients who received intravenous recombinant tissue plasminogen activator and had…
Comparison
Prior use of antiplatelet agents or… vs No prior use of antiplatelet agents
Design
Cohort
Authors
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Supports not deferring IV rt-PA for prior antiplatelet use; hypothesis-generating and requires prospective validation.
Does prior antiplatelet use affect recanalization rate and outcome in acute ischemic stroke patients receiving IV rt-PA?
Prior antiplatelet use does not significantly impact recanalization rates or long-term outcomes in acute stroke patients receiving IV rt-PA, suggesting it should not defer thrombolytic treatment.
Ibrahim et al. (2010) studied this question.
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