Grave Sequelae of Blood Transfusions; A Clinical Study of 13 Cases Occurring in 3500 Blood Transfusions

Article1 April 1938GRAVE SEQUELAE OF BLOOD TRANSFUSIONS; A CLINICAL STUDY OF 13 CASES OCCURRING IN 3500 BLOOD TRANSFUSIONSELMER L. DEGOWIN, M.D.ELMER L. DEGOWIN, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-11-10-1777 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptBy the year 1910, the contributions to our knowledge of isohemagglutination made by Landsteiner, Shattock, Hektoen, Janský, Moss, and others had laid the foundation for a great reduction in mortality from the transfusion of blood. The introduction of citrated blood by Agote, Weil, and Lewisohn during the World War, provided a much simpler method than had been in previous use. As a result of the reduction in hazards and the increase in technical facility, blood transfusion has become a common therapeutic procedure. The ease of administration and the relatively small mortality have unfortunately impressed many operators only with the innocuousness...Bibliography1. POLAYESLEDERER SHM: Reactions to blood transfusion. Observations from 2,500 transfusions with a review of the literature, Jr. Lab. and Clin. Med., 1932, xvii, 1029-1043. Google Scholar2. TERPLANJAVERT KLCT: Fatal hemoglobinuria with uremia from quinine in early pregnancy, Jr. Am. Med. Assoc., 1936, cvi, 529-532. CrossrefGoogle Scholar3. BORDLEY J: Reactions following transfusion of blood with urinary suppression and uremia, Arch. Int. Med., 1931, xlvii, 288-315. CrossrefGoogle Scholar4. BAKERDODDS SLEC: Obstruction of the renal tubules during the excretion of hemoglobin, Brit. Jr. Exper. Path., 1925, vi, 247-260. Google Scholar5. DEGOWINOSTERHAGENANDERSCH ELHFM: Renal insufficiency from blood transfusion. I. Relation to urinary acidity, Arch. Int. Med., 1937, lix, 432-444. CrossrefGoogle Scholar6. BROWNEUSTERMANHARTMANROWNTREE GEGBHRLG: Toxic nephritis in pyloric and duodenal obstruction. Renal insufficiency complicating gastric tetany, Arch. Int. Med., 1923, xxxii, 425-455. CrossrefGoogle Scholar7. LONGCOPERACKEMANN WTFM: Severe renal insufficiency associated with attacks of urticaria in hypersensitive individuals, Jr. Urol., 1917, i, 351-366. CrossrefGoogle Scholar8. MASONMANN JBFC: Effect of hemoglobin on volume of the kidney, Am. Jr. Physiol., 1931, xcviii, 181-185. CrossrefGoogle Scholar9. HESSEFILATOV EA: Experimentelle Untersuchungen über das Wesen des hämolytischen Shocks bei der Bluttransfusion und die therapeutische Beeinflussung desselben. I. Die Nierenfunktionsstörungen im akuten Experiment, Ztschr. f. d. ges. exper. Med., 1933, lxxxvi, 211-230. CrossrefGoogle Scholar10. GOLDRINGGRAEF WI: Nephrosis with uremia following transfusion with incompatible blood, Arch. Int. Med., 1936, lviii, 825-845. (Author's Case 7.) CrossrefGoogle Scholar11. POLAYES SH: Ibid., page 1037. Google Scholar12. HANSEN-PRUSSMILLER OCBN: Uremia following blood transfusion, Southern Med. Jr., 1936, xxix, 1033-1035. CrossrefGoogle Scholar13. LICHTYHAVILLWHIPPLE JAWHGH: Renal thresholds for hemoglobin in dogs, Jr. Exper. Med., 1932, lv, 603-615. CrossrefGoogle Scholar14. DRABKINWIDERMANLANDOW DLAHH: Fate of hemoglobin injected into the blood stream, Jr. Biol. Chem., 1935, cix, xxvii-xxviii. Google Scholar15. DEGOWINBALDRIDGE ELCW: Fatal anuria following blood transfusion, Am. Jr. Med. Sci., 1934, clxxxviii, 555-560. (Cases 1 and 2 reported in detail.) CrossrefGoogle Scholar16. VON DEESTENCOSGROVE HTSA: Renal insufficiency following blood transfusion—recovery after venesection, ANN. INT. MED., 1933, vii, 105-108. Google Scholar17. HAYESPARAMORE DSRH: Anuria treated with spinal anesthesia, Lancet, 1935, ii, 554-556. CrossrefGoogle Scholar18. BANCROFT FW: Anuria following transfusion. Effect of decapsulation of both kidneys, Ann. Surg., 1925, lxxxi, 733-738. CrossrefGoogle Scholar19. HESSEFILATOV EA: Die klinische Bestätigung der Möglichkeit der Behandlung des hämolytischen Shocks bei der Bluttransfusion nach unserer Method, Zentralbl. f. Chir., 1933, lx, 851-854. Google Scholar20. DEGOWIN EL: Hemolytic transfusion reaction produced by the blood of a "universal donor," Jr. Am. Med. Assoc., 1937, cviii, 296, 297. (Case 8 reported in detail.) CrossrefGoogle Scholar21. WIENER AS: Blood groups and blood transfusion, 1935, Charles C. Thomas, Springfield, page 61. Google Scholar22. PLUMMER NS: Blood transfusion. A report of six fatalities, Brit. Med. Jr., 1936, ii, 1186-1189. CrossrefGoogle Scholar23. SCHALY GA: Retinal hemorrhage after transfusion of blood, Nederl. Tijdschr. v. Geneesk., 1926, i, 965-968. Abstracted in Jr. Am. Med. Assoc., 1926, lxxxvi, 1955. Google Scholar24. MESSINGERECKSTEIN HCAW: Retinal hemorrhages after blood transfusion, Rhode Island Med. Jr., 1931, xiv, 171-175. Google Scholar25. WALKER GL: Personal communication. Google Scholar26. MANNBOLLMAN FCJL: Jaundice, Jr. Am. Med. Assoc., 1935, civ, 371-374. CrossrefGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Iowa City, Iowa*Received for publication October 15, 1937.From the Department of Internal Medicine, State University of Iowa Medical College, Iowa City. Nextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byTransfusion-associated circulatory overload and transfusion-related acute lung injuryTHE COMPLICATIONS OF BLOOD TRANSFUSIONHemodynamic Effects of Blood Transfusion in Chronic AnemiaReferencesCirculatory overloading during and following blood transfusion∗Rh and Other Blood GroupsThe Influence of Transfusion Velocity on the Occurrence and Rate of ReactionsHemoglobinemia and the HemoglobinuriasAnuria: With special reference to renal failure in blackwater fever, incompatible transfusions, and crush injuriesBlood transfusions in pregnancyThe compatibility factor in the transfusion of bloodThe treatment of oliguria and anuriaA new method of conserving blood for transfusion purposes 1 April 1938Volume 11, Issue 10Page: 1777-1791KeywordsBloodBlood transfusionMortality ePublished: 1 December 2008 Issue Published: 1 April 1938 Copyright & PermissionsCopyright, 1938, by The American College of PhysiciansPDF downloadLoading ...