Temperature-Sensitive Mutations Indrosophila Melanogaster: Xx. Lethality Due to Translocations

In a group of 10 γ-ray-induced temperature-sensitive (ts) lethal mutations on the X chromosome of Drosophila melanogaster, three were found to inhibit crossing over on this element. Subsequent studies showed that these three ts lethal mutations are associated with X [Formula: see text] autosome translocations. Developmental analysis has revealed that the patterns of temperature-sensitivity and lethality are similar to those found in other ts mutations. One of the mutations (T(X;2)X9 ts ) is unique, however, in that only males exhibit temperature-sensitive lethality while homozygous females are unaffected by a change in temperature. It is proposed that these three mutations may be exhibiting some new type of "position effect".