Why the study?
Enteroviral hepatitis has rarely been recorded in pediatric populations other than neonates.
Enteroviral infection can cause self-limiting acute hepatitis in pediatric patients presenting with hand-foot-and-mouth disease, and should be considered in the differential diagnosis of acute hepatitis of unknown origin.
Answers are grounded in this paper and cite their sources.
Alerts clinicians to enteroviral hepatitis beyond neonates; extends sparse pediatric reports but leaves open incidence and management.
Enteroviruses are a common cause of infection in neonates, causing wide spectrum of diseases, including myocarditis, myelitis, meningoencephalitis, hepatitis, and sepsis. The enteroviral hepatitis has rarely been recorded in pediatric populations other than neonates. We report a rare case of self-limiting acute hepatitis in a healthy 3-year-old child affected by hand-foot-and-mouth disease caused by Enterovirus. Providers should be aware of hepatitis prevalence in the Enteroviral infection, and should consider it in the differential diagnosis for acute hepatitis of unknown origin.
No takes yet. Share an insight, caveat, or question.
Fenza et al. (2025) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: