Four variants of human erythrocyte lactate dehydrogenase (LDH) are described. One of these is similar to the one previously described by Boyer and is interpreted as a variant of LDH-B. The other three are thought to represent variants of LDH-A. Studies of families indicate that LDH-A and LDH-B are under separate genetic control and are inherited as autosomal co-dominants. Evidence is presented that the LDH-A locus is not closely linked to the loci for the ABH and Duffy blood group systems.
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Kraus et al. (1964) studied this question.
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