Why the study?
Does early fibrinolysis after cardiopulmonary bypass predict poor outcomes in adults undergoing cardiac surgery?
Population
142 adults who had undergone cardiac surgery with cardiopulmonary bypass
Comparison
Evidence of fibrinolysis vs Non-fibrinolytic patients
Design
Cohort
Follow-up
intensive care stay
Authors
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May warrant vigilance for instability after CPB; leaves open whether early fibrinolysis is causal or a surrogate marker.
Does early fibrinolysis after cardiopulmonary bypass predict poor outcomes in adults undergoing cardiac surgery?
Early fibrinolysis after cardiopulmonary bypass is associated with increased need for hemodynamic support and higher mortality, suggesting it may be an early marker of systemic inflammation syndrome.
Cvachovec et al. (2000) studied this question.
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