Population
Unanesthetized rats undergoing cervical spinal transection (CST)
Comparison
Autonomic ganglionic blockade, alpha-adrenergic… vs Baseline/control levels
Design
Preclinical
Follow-up
9 days
Authors
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Angiotensin II supports post-transection pressure maintenance in rats; extends mechanistic insight but leaves human translation open.
In a rat model of cervical spinal transection, angiotensin II vasoconstrictor actions are important for arterial pressure maintenance, but not responsible for its normalization over time.
Osborn et al. (1989) studied this question.
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