October 1, 1995The Journal of PhysiologyOpen Access

Effects of hypothalamic thermal stimuli on sympathetic neurones innervating skin and skeletal muscle of the cat hindlimb.

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Population

Anaesthetized and artificially ventilated cats

Design

Preclinical

Authors

Discussion

Hypothalamic CVC inhibition in rats supports pathway mapping; leaves open human thermoregulatory translation.

Population

Anaesthetized and artificially ventilated cats

Intervention

Thermal stimuli (warming and cooling) applied to the anterior hypothalamus and spinal cord

Outcome

Activity of postganglionic neurones (cutaneous vasoconstrictor [CVC], muscle vasoconstrictor [MVC], and sudomotor [SM] neurones)surrogate

Hypothalamic warming specifically inhibits cutaneous vasoconstrictor neurones, indicating a highly specific central pathway for thermoregulation.

Grewe et al. (1995) studied this question.

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