Lipid Changes Around the Final Menstrual Period Predict Carotid Subclinical Disease in Postmenopausal Women
Why the study?
Do lipid changes around the final menstrual period predict carotid subclinical disease in postmenopausal women?
Population
863 natural postmenopausal women with no history of heart attack or stroke
Design
Cohort
Follow-up
12 or 13 years
Authors
Discussion
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Member takes
Implication
Perimenopausal LDL rises associate with carotid plaque; hypothesis-generating for targeted interventions, prospective trials needed.
Structured PICO
Do lipid changes around the final menstrual period predict carotid subclinical disease in postmenopausal women?
P
Population
863 natural postmenopausal women with no history of heart attack or stroke
I
Intervention
Lipid changes around the final menstrual period (FMP)
O
Outcome
Carotid intima-media thickness, interadventitial diameter, and plaquesurrogate
Atherogenic lipid changes around the final menstrual period are associated with increased subclinical carotid atherosclerosis in postmenopausal women.
Cite This Study
Matthews et al. (2016) studied this question.