The 18-kDa form of the L* protein, translated via an unusual internal ribosome entry site mechanism, is required for efficient persistence of Theiler's virus in the central nervous system.
No takes yet. Share an insight, caveat, or question.
Cautions against clinical translation from murine models; leaves open whether targeting 18-kDa L* informs human CNS viral persistence.
Eyll et al. (2002) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: