Why the study?
Does adenoviral gene transfer with human apolipoprotein A-I reduce vascular inflammation and fibrosis in ob/ob mice?
Does adenoviral gene transfer with human apolipoprotein A-I reduce vascular inflammation and fibrosis in ob/ob mice?
Apo A-I gene transfer increases HDL-cholesterol and reduces vascular inflammation and fibrosis in an ob/ob mouse model of obesity.
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ApoA-I gene transfer may attenuate vascular fibrosis in obese mice; hypothesis-generating for human translation.
Spillmann et al. (2016) studied this question.
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