Key points are not available for this paper at this time.
Answers are grounded in this paper and cite their sources.
Lower aldosterone predicted mortality in hypertensive HD patients; hypothesis-generating and should not yet change practice.
Kohagura K, Higashiuezato Y, Ishiki T, et al : Plasma aldosterone in hypertensive patients on chronic hemodialysis: distribution, determinants and impact on survival. Hypertens Res 2006; 29 : 597–604. Article CAS Google Scholar Diskin CJ, Stokes TJ, Dansby LM, Carter TB, Radcliff L : The clinical significance of aldosterone in ESRD: Part II. Nephrol Dial Transplant 2004; 19 : 1331–1332; author reply 1332. Article CAS Google Scholar Fernandez RG, Leehan JA, Pastrana RF, Muniz RO : Effect of malnutrition on K + current in T lymphocytes. Clin Diagn Lab Immunol 2005; 12 : 808–813. CAS PubMed PubMed Central Google Scholar Schlaich MP, Schobel HP, Hilgers K, Schmieder RE : Impact of aldosterone on left ventricular structure and function in young normotensive and mildly hypertensive subjects. Am J Cardiol 2000; 85 : 1199–1206. Article CAS Google Scholar Rocha R, Chander PN, Khanna K, Zuckerman A, Stier CT Jr : Mineralocorticoid blockade reduces vascular injury in stroke-prone hypertensive rats. Hypertension 1998; 31 : 451–458. Article CAS Google Scholar Sato A, Funder JW, Saruta T : Involvement of aldosterone in left ventricular hypertrophy of patients with end-stage renal failure treated with hemodialysis. Am J Hypertens 1999; 12 : 867–873. Article CAS Google Scholar Endemann DH, Touyz RM, Iglarz M, Savoia C, Schiffrin EL : Eplerenone prevents salt-induced vascular remodeling and cardiac fibrosis in stroke-prone spontaneously hypertensive rats. Hypertension 2004; 43 : 1252–1257. Article CAS Google Scholar Sato A, Saruta T : Aldosterone-induced organ damage: plasma aldosterone level and inappropriate salt status. Hypertens Res 2004; 27 : 303–310. Article CAS Google Scholar Download references
No takes yet. Share an insight, caveat, or question.
Kohagura et al. (2007) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: