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January 1, 2008Hypertension ResearchOpen Access

Effects of Glucose Metabolism on Aortic Pulse Wave Velocity in Hemodialysis Patients with and without Diabetes

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Why the study?

Does glucose metabolism affect aortic stiffness in hemodialysis patients with and without diabetes?

Population

242 stably treated hemodialysis (HD) patients, including 94 with diabetes

Comparison

Diabetes status and glucose metabolism vs Hemodialysis patients without diabetes

Design

Cross-sectional

Authors

TMTomoji MatsumaeMemorial Hospital of South BendYAYasuhiro AbeNational Institute of Health SciencesGMGenji MURAKAMI

Discussion

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Implication

May inform glycemic targets in hemodialysis; extends observations to nondiabetics but leaves causality open.

Structured PICO

Does glucose metabolism affect aortic stiffness in hemodialysis patients with and without diabetes?

P
Population
242 stably treated hemodialysis (HD) patients, including 94 with diabetes
I
Intervention
Diabetes status and glucose metabolism (HbA1c levels)
C
Comparator
Hemodialysis patients without diabetes
O
Outcome
Aortic stiffness assessed by measuring carotid-femoral pulse wave velocity (cfPWV)surrogate

Glucose metabolism and hyperglycemia strongly contribute to aortic stiffness in hemodialysis patients, regardless of diabetes status.

Cite This Study

Matsumae et al. (2008) studied this question.

synapsesocial.com/papers/6a854b33734852141cd4c43chttps://doi.org/10.1291/hypres.31.1365
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Also Consider

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