The longitudinal muscle of an isolated Remak nerve‐rectum preparation from the chicken responded to nerve stimulation with a contraction or, when the tone of the preparation was raised by acetyl‐β‐methylcholine (11·0 mM), with a contraction followed by a relaxation. The relaxation of the preparation was unaffected by hexamethonium, antagonized by bretylium, blocked by a combination of propranolol and phentolamine at specific concentrations and was absent or diminished in reserpinised preparations. The contraction was abolished by hexamethonium or tubocurarine and was partially antagonized by hyoscine.
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Bartlet et al. (1971) studied this question.
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