Why the study?
Does Adenovirus etiology affect clinical and pulmonary function findings in children with postinfectious bronchiolitis obliterans compared to unknown etiology?
Population
58 children with postinfectious bronchiolitis obliterans (PIBO), median age 8 years, male/female ratio 3.4:1.
Comparison
Adenovirus (+) etiology (Group 1) vs No etiologic agent identified (Group 2)
Design
Cohort
Authors
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Adenovirus status may not inform prognosis or management in postinfectious bronchiolitis obliterans; leaves open etiology-specific mechanisms for future study.
Does Adenovirus etiology affect clinical and pulmonary function findings in children with postinfectious bronchiolitis obliterans compared to unknown etiology?
Adenovirus etiology does not appear to significantly alter the severe obstructive pulmonary function sequelae in children with postinfectious bronchiolitis obliterans compared to unknown etiologies.
Aguerre et al. (2010) studied this question.