Why the study?
It remained unclear whether fatty acid metabolism of brown adipose tissue differs between lean and obese healthy humans.
Is basal and cold-induced fatty acid uptake of human brown adipose tissue impaired in obese compared to lean healthy humans?
Population
Lean and obese healthy human subjects
Comparison
Cold exposure vs room temperature
Authors
Loading...
Obesity associated with blunted BAT fatty acid uptake; hypothesis-generating for BAT-targeted therapies in metabolic disease.
Is basal and cold-induced fatty acid uptake of human brown adipose tissue impaired in obese compared to lean healthy humans?
Obesity is associated with blunted fatty acid metabolism and less active brown adipose tissue in both basal and cold-activated states.
Saari et al. (2020) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: