Population
Tumor cells in vitro and in vivo models
Design
Preclinical
Authors
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Supports ion channel targeting in cancer; hypothesis-generating from animal data and requires clinical validation.
A rationally designed monoclonal antibody against the hEag1 potassium channel inhibits tumor growth, providing proof of concept for targeting ion channels in cancer therapy.
Gómez‐Varela et al. (2007) studied this question.
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