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Solving the puzzle: The correct structure and configuration of the natural product gephyronic acid has been determined by NMR analysis and correlation with synthetic reference compounds, as well as with myriaporone 4 and tedanolide. Gephyronic acid, isolated from culture supernatants of Archangium gephyra, displays intriguing antibiotic activity.
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Nicolas et al. (2010) studied this question.
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