Population
In-vitro mock circulation model in aortic position using enzyme-activated milk to resemble blood clotting…
Design
Preclinical
Authors
Loading...
Remote thrombus sites may guide mechanical valve redesign; leaves open whether modifications reduce early thrombosis in vivo.
In-vitro modeling of bileaflet mechanical heart valves reveals that initial thrombus formation occurs downstream of the leaflets near the orifice ring, with a significant portion located remote from the hinge region, which may inform future valve design.
Scharfschwerdt et al. (2008) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: