Population
Rigid-walled model of normal and stenosed aortic valves placed in a pulsatile water-tunnel
Comparison
Aortic valve stenosis (modeled) vs Normal aortic valve (modeled)
Design
Preclinical
Authors
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May reduce coronary perfusion pressure in aortic stenosis; leaves open clinical relevance and requires human validation.
In vitro modeling demonstrates that aortic stenosis disrupts normal vortex formation in the aortic sinuses, leading to turbulent jets and reduced coronary perfusion pressure.
B. J. Bellhouse (1969) studied this question.
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