What question did this study set out to answer?

To report a rare adverse presentation of severe, transient paradoxical agitation triggered by low-dose etomidate during procedural sedation.

August 19, 2026Journal of Pharmacy Practice

Paradoxical Agitation Following Etomidate Sedation for Electrical Cardioversion: A Case Report

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Authors

MPM K PalmerBoston University ECEmma Chee-HowUniversity of Alabama at Birmingham COCallie O’BryantUniversity of Alabama at Birmingham

Discussion

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Implication

Case report observes severe, transient agitation following low-dose etomidate sedation in a patient undergoing electrical cardioversion, highlighting a rare adverse neuropsychiatric reaction.

Key Points

To report a rare adverse presentation of severe, transient paradoxical agitation triggered by low-dose etomidate during procedural sedation.
Case report of a healthy young adult presenting with new-onset atrial fibrillation undergoing electrical cardioversion.
Administered low-dose intravenous etomidate to achieve procedural sedation.
Administration of low-dose etomidate induced sudden, severe paradoxical agitation rather than standard sedation.
The neuropsychiatric agitation was transient and self-limiting, resolving shortly after the procedure.

Cite This Study

Palmer et al. (2026) studied this question.

synapsesocial.com/papers/6a85634f03308d306e2d6545 https://doi.org/10.1177/08971900261477883

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Implication

Case report observes severe, transient agitation following low-dose etomidate sedation in a patient undergoing electrical cardioversion, highlighting a rare adverse neuropsychiatric reaction.

Paradoxical Agitation Following Etomidate Sedation for Electrical Cardioversion: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

Paradoxical Agitation Following Etomidate Sedation for Electrical Cardioversion: A Case Report

Discussion

Member takes

Implication

Key Points

Cite This Study

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