Key result
Facial plaque-type cutaneous sarcoidosis is linked to the presence of cardiac sarcoidosis.
Why the study?
Cardiac involvement in sarcoidosis is clinically crucial due to its impact on prognosis, but few reports have examined the association between cutaneous manifestations and cardiac sarcoidosis.
Observational (n=111)
No
Facial plaque-type cutaneous sarcoidosis may serve as a useful clinical sign for identifying underlying cardiac involvement in patients with sarcoidosis.
May support cardiac screening in facial plaque-type cutaneous sarcoidosis; leaves open need for prospective validation.
Sarcoidosis affects various organs, with cardiac involvement being clinically crucial due to its impact on prognosis. To date, there have been few reports on the association between cutaneous manifestations and cardiac sarcoidosis. We retrospectively examined 111 patients with cutaneous sarcoidosis and identified cardiac sarcoidosis in 16 patients (14.4%, 4 males and 12 females). The skin lesions were plaque (n = 7), nodular (n = 4), subcutaneous (n = 3), scar (n = 3), and lupus pernio (n = 1) types. A statistically significant correlation was observed between facial plaque-type cutaneous sarcoidosis and cardiac sarcoidosis. Although the examined number is small, our results suggest that plaque-type sarcoidosis in the face may be a useful sign for considering cardiac involvement. Further studies are necessary to elucidate the association of cutaneous and cardiac sarcoidosis.
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Mukaiyama et al. (2026) conducted an observational in Cutaneous sarcoidosis (n=111). Facial plaque-type cutaneous sarcoidosis was evaluated on Presence of cardiac sarcoidosis. Facial plaque-type cutaneous sarcoidosis was significantly correlated with the presence of cardiac sarcoidosis in a retrospective cohort of 111 patients.
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