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Positive latex fixation tests were observed in relation to sarcoidosis, kala azar and liver disease without concomitant rheumatoid arthritis. Ultracentrifugation of sera from these patients revealed the presence of a heavy gamma globulin resembling rheumatoid factor. Amboceptor‐sensitized sheep cell tests were uniformly negative except in the one case of liver disease.
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Kunkel et al. (1958) studied this question.
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