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August 19, 2026MicroOpen Access

From Nano to Smile: Applications, Innovations, and the Future of Nanotechnology in Dentistry—A Scoping Review

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Authors

RSRajashekhara Bhari SharaneshaDVDeepti VirupakshappaMAMaram Alagla

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Overview

Scoping review demonstrates diverse nanotechnology applications across dental specialties, highlighting the need for standardized safety evaluation and regulatory frameworks.

Key Points

  • To review the scope, major developments, emerging innovations, and translational challenges of nanotechnology across all dental specialties.
  • Followed Joanna Briggs Institute (JBI) methodology and PRISMA-ScR guidelines using the PCC framework.
  • Searched PubMed/MEDLINE, Scopus, and Web of Science for English-language primary research and reviews without date restrictions.
  • Screened titles, abstracts, and full texts, resulting in the inclusion of N=133 studies.
  • Applications spanned restorative dentistry, implantology, periodontology, endodontics, prosthodontics, orthodontics, oral diagnostics, antimicrobial therapies, and tissue regeneration.
  • Silver nanoparticles (AgNPs), calcium phosphate nanoparticles (CaP NPs), and polymeric nanoparticles (PLGA, chitosan) were the most frequently reported materials.
  • Publication volume increased noticeably from 2019 onward, with translational barriers identified around nanotoxicology, standard characterization, and international regulatory harmonization.

Cite This Study

Sharanesha et al. (2026) studied this question.

synapsesocial.com/papers/6a8563fe03308d306e2d7741https://doi.org/10.3390/micro6030068
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