Why the study?
The study was conducted to analyze the association of preoperative C-reactive protein levels with postoperative complications in elderly patients undergoing surgeries for femoral neck fracture.
Does elevated preoperative CRP level predict postoperative complications in elderly patients undergoing surgeries for femoral neck fracture?
Does elevated preoperative CRP level predict postoperative complications in elderly patients undergoing surgeries for femoral neck fracture?
Elevated preoperative CRP levels (≥40 mg/L) are associated with a nearly 4-fold increased risk of postoperative complications in elderly patients undergoing surgery for femoral neck fracture.
Answers are grounded in this paper and cite their sources.
May support preoperative CRP for risk stratification in elderly femoral neck fracture surgery; leaves open whether interventions improve outcomes.
OBJECTIVE: To analyze the association of preoperative C-reactive protein (CRP) level with postoperative complications in elderly patients undergoing surgeries for femoral neck fracture. METHODS: We retrospectively analyzed the data of 147 elderly patients (median age 80 years; 73.5% of the patients were female) undergoing surgeries for femoral neck fracture. According to preoperative CRP level, the patients were divided into normal CRP (< 10 mg/L) group (31 patients), mild elevation group (CRP level of 10-40 mg/L; 51 patients), and severe elevation group (CRP ≥40 mg/L; 65 patients). The association of preoperative CRP levels with postoperative complications was analyzed. RESULTS: : 1.47-16.26), respectively. CONCLUSIONS: Preoperative CRP level has a dose-response relationship with complications in elderly patients following arthroplasty for femoral neck fracture, and the patients with a preoperative CRP level ≥40 mg/L are exposed to a significantly increased risk for postoperative complications by 3.89 folds compared with the patients with a normal CRP level.
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Zhao et al. (2019) studied this question.
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