Key result
Preoperative CRP levels ≥2 mg/dl were independently associated with a combined endpoint of SIRS and atrial fibrillation, kidney failure, shock, or death (OR 2.95; 95% CI 1.20-7.23; p<0.018).
Why the study?
Does elevated preoperative C-reactive protein (≥2 mg/dl) predict systemic inflammatory response syndrome and postoperative complications in patients undergoing cardiovascular surgery?
Cohort (n=169)
Does elevated preoperative C-reactive protein (≥2 mg/dl) predict systemic inflammatory response syndrome and postoperative complications in patients undergoing cardiovascular surgery?
Odds Ratio: 2.95 (95% CI 1.2–7.23)
p-value: p=<0.018
Elevated preoperative CRP levels (≥2 mg/dl) are independently associated with an increased risk of systemic inflammatory response syndrome and other postoperative complications following cardiovascular surgery.
No takes yet. Share an insight, caveat, or question.
Elevated preoperative CRP was associated with complications after cardiovascular surgery; hypothesis-generating and should not yet change practice.
Waldman et al. (2011) conducted a cohort in Cardiovascular surgery (n=169). Preoperative C-reactive protein (CRP) ≥2 mg/dl vs. Preoperative CRP <2 mg/dl was evaluated on Combined endpoint including the incidence of systemic inflammatory response syndrome and its association with atrial fibrillation, kidney failure, shock or death (OR 2.95, 95% CI 1.20-7.23, p=<0.018). Preoperative CRP levels ≥2 mg/dl were independently associated with a combined endpoint of SIRS and atrial fibrillation, kidney failure, shock, or death (OR 2.95; 95% CI 1.20-7.23; p<0.018).
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