Key result
Radial artery grafts demonstrated similar long-term occlusion rates compared to saphenous vein grafts (18.4% vs 16.4%) at a mean follow-up of 8.9 years.
Why the study?
To aid rational graft selection in coronary artery bypass surgery, the relative long-term merits of radial artery and saphenous vein grafts needed evaluation using a gold standard method with minimal selection bias.
Does radial artery graft improve long-term graft patency compared to saphenous vein graft in patients undergoing coronary artery bypass grafting?
RCT (n=76)
Does radial artery graft improve long-term graft patency compared to saphenous vein graft in patients undergoing coronary artery bypass grafting?
Absolute Event Rate: 18.4% vs 16.4%
Long-term (8-12 years) angiographic follow-up shows similar patency rates between radial artery and saphenous vein grafts, challenging the preferential use of radial artery conduits.
Similar patency rates do not support preferential radial use in CABG; hypothesis-generating and should not yet change practice.
Objectives: The benefits of coronary artery bypass surgery depend on lasting graft patency. To aid rational graft selection, the relative long-term merits of radial artery and saphenous vein grafts need to be determined by a gold standard method and with minimal clinically driven selection bias. Methods: The patency rates of various conduits were determined by direct angiography in 76 patients from a cohort of 119 undergoing coronary artery bypass grafting 7.6–12.1 (mean 8.9) years before. Results: 14 out of 76 radial artery and 10 out of 61 saphenous vein grafts were occluded (rates 0.18 and 0.16, respectively). Conclusion: The high long-term patency rate of saphenous vein grafts does not support a preferential use of the radial artery as a coronary artery bypass conduit. Clinical registration number: ISRCTN23118170
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Bahar et al. (2020) conducted an RCT in Coronary artery disease requiring bypass surgery (n=76). Radial artery graft vs. Saphenous vein graft was evaluated on Graft occlusion. Radial artery grafts demonstrated similar long-term occlusion rates compared to saphenous vein grafts (18.4% vs 16.4%) at a mean follow-up of 8.9 years.
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