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December 17, 2010European Journal of Cardio-Thoracic Surgery

Radial artery versus saphenous vein conduits for coronary artery bypass surgery: forty years of competition — which conduit offers better patency? A systematic review and meta-analysis

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Why the study?

Do radial artery conduits improve angiographic graft patency compared to saphenous vein conduits in patients undergoing coronary artery bypass surgery?

Population

Patients undergoing coronary artery bypass surgery for multivessel disease requiring additional grafts

Comparison

Radial artery conduits vs Saphenous vein conduits

Design

Meta-analysis

Follow-up

up to >5 years (stratified as ≤1 year, 1-5 years, >5 years)

Authors

TAThanos AthanasiouCardiac SurgerySSSrdjan SasoImperial College Healthcare NHS TrustCRChristopher RaoUniversity of Illinois Urbana-Champaign

Discussion

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Implication

Supports radial artery preference over saphenous vein in CABG; confirms meta-analytic superiority for long-term patency.

Structured PICO

Do radial artery conduits improve angiographic graft patency compared to saphenous vein conduits in patients undergoing coronary artery bypass surgery?

P
Population
Patients undergoing coronary artery bypass surgery for multivessel disease requiring additional grafts (35 studies included)
I
Intervention
Radial artery conduits
C
Comparator
Saphenous vein conduits
O
Outcome
Angiographic graft patency stratified over different follow-up intervals (early ≤ 1 year, medium-term 1-5 years, and long-term >5 years)surrogate

Radial artery conduits offer superior medium- and long-term angiographic patency compared to saphenous vein grafts in coronary artery bypass surgery.

Limitations

  • Heterogeneity due to angiographic patency characteristics
  • Risk of bias

Cite This Study

Athanasiou et al. (2010) studied this question.

synapsesocial.com/papers/6a727e0df44fa9f079dff531https://doi.org/10.1016/j.ejcts.2010.11.012
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The fate of the radial artery conduit in coronary artery bypass grafting surgery2006 · 43 citations
  2. 2Diabetes and survival after coronary artery bypass grafting: comparison with an age- and sex-matched population2009 · 38 citations
  3. 3Nitric Oxide Is Responsible for Flow-Dependent Dilatation of Human Peripheral Conduit Arteries In Vivo1995 · 1,626 citations
  4. 4The Chinese coronary artery bypass grafting registry study: analysis of the national multicentre database of 9248 patients2008 · 30 citations
  5. 5Angiographic evaluation of the luminal changes in the radial artery graft in coronary artery bypass surgery: a concern over the long-term patency2002 · 34 citations