Answers are grounded in this paper and cite their sources.
This paper reviews the sequence of histomorphologic changes that occur in and around a fracture site, and discusses recent concepts about the roles of the cells and bone matrical moieties in promoting specific cell transformations during the phases of callus tissue formation and consolidation of the bony cortex. Current knowledge about the roles of autocrine, paracrine, and endocrine polypeptide growth and transforming factors lends new perspectives about this classic problem in bone physiology.
No takes yet. Share an insight, caveat, or question.
David J. Simmons (1985) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: