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Randomized trial demonstrates consistent muscle strength gains from krill oil across demographic subgroups in older adults, suggesting broad benefits despite sex-specific neuromuscular differences.
). Increases in muscle strength, size, and physical function in response to krill oil supplementation were comparable across age, sex and BMI subgroups (all P > 0.05). This was similar for neuromuscular measures although increases in the Mwave the response to krill oil supplementation differed by sex, with no change over time in females in either krill or control groups, but an increase in Mwave in males in the krill group (+3.80 [1.72-5.88] mV, p = 0.016) with a tendency for a decrease in the control group (-3.71 [1.58-6.05] mV, p = 0.059). In conclusion, krill oil supplementation improved muscle strength and size in older adults regardless of age, sex and BMI status, although neuromuscular effects of krill oil on membrane excitability, via the Mwave, may be more pronounced in men. ClinicalTrials.gov Identifier: NCT04048096.
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Hayman et al. (2025) studied this question.
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