Biological and social perspectives on clonorchiasis, a current nosology of the Far East and Southeast Asia (material for preparing the lecture)

Clonorchiasis is a widespread natural focal biohelminthiasis. On the globe this pathology is registered in 19 million people. Annually more than 50% of cases in Russia fall on the regions of the Far Eastern Federal District: Amur Region, Khabarovsk Territory and Primorye. The aim of the study was to systematically analyze publications on the problem of clonorchiasis. Material and methods. Based on the materials of the scientometric databases Web of Sciences, Scopus, PubMed, eLIBRARY, articles were searched using the following keywords: clonorchiasis, morbidity, endemic foci, epidemiology, prevention. 83 sources were found, from which 56 articles were selected. An analysis of information on the epidemiology and social factors determining the incidence of clonorchiasis was carried out. Results and discussion. The features of biology and adaptation of *Сlonorchis sinensis* in the system “parasite – definitive and intermediate hosts” are presented. The role of natural-biological and social factors determining endemic morbidity of clonorchiasis in the population was analyzed. The questions of diagnostics, treatment and prophylaxis were considered. Conclusion. Within the framework of preventive work it is necessary to integrate the efforts of parasitologists, veterinarians, ecologists, geneticists, sanitary supervision services, faculty members of medical and biological universities, employees of municipal bodies, food industry workers.