Why the study?
Does severe depression alter cardiovascular and autonomic responses to brief psychosocial stress in patients without heart disease?
Population
50 subjects without heart disease, comprising 25 severely depressed subjects and 25 non-depressed controls.
Comparison
Brief psychosocial stress tasks including anger… vs Non-depressed control group undergoing the same…
Design
Case-control
Authors
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Severe depression was associated with reduced HF-HRV and altered reactivity without heart disease; hypothesis-generating for autonomic links to CV risk.
Does severe depression alter cardiovascular and autonomic responses to brief psychosocial stress in patients without heart disease?
Severe depression is associated with impaired cardiac autonomic functioning and altered cardiovascular reactivity to psychosocial stress, even in the absence of structural heart disease.
Ehrenthal et al. (2010) studied this question.
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