Answers are grounded in this paper and cite their sources.
Ethanol enhances expression of cell surface class I major histocompatibility complex (MHC) antigens in a variety of cell lines; up to an eightfold increase is observed in an embryonic cell line. In ethanol‐treated L cells, increased cell surface expression of MHC antigens occurs with a concomitant increase in steady‐state RNA levels. This effect is promoter dependent and restricted, because not all gene products are elevated. The effective ethanol concentration (1%) is physiologically attainable, leading to speculations about the role of elevated MHC antigens in alcohol‐related diseases.— P arent , L. J.; E hrlich , R.; M atis , L.; S inger , D. S. Ethanol: an enhancer of major histocompatibility complex antigen expression. FASEB J. 1: 469‐473; 1987.
No takes yet. Share an insight, caveat, or question.
Parent et al. (1987) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: