Key result
Annuloplasty with the IMR ETlogix ring for ischemic mitral regurgitation significantly increased mitral mean gradient during exercise compared to rest (7.8 vs 3.3 mmHg, p<0.001).
Why the study?
Does annuloplasty with an IMR ETlogix ring effectively correct mitral regurgitation without inducing mitral stenosis in patients with chronic ischemic mitral regurgitation?
Observational (n=40)
Does annuloplasty with an IMR ETlogix ring effectively correct mitral regurgitation without inducing mitral stenosis in patients with chronic ischemic mitral regurgitation?
While IMR ETlogix ring annuloplasty effectively corrects chronic ischemic mitral regurgitation, it significantly increases the mitral mean gradient during exercise, suggesting it may induce functional mitral stenosis.
Answers are grounded in this paper and cite their sources.
Raises concern for exercise-induced functional mitral stenosis after IMR ETlogix annuloplasty; hypothesis-generating for ring selection in ischemic MR.
OBJECTIVES: Ring annuloplasty combined with coronary artery bypass grafting is the standard approach for treatment of patients with ischemic mitral regurgitation. We evaluated mitral valve hemodynamic performance and recurrence of mitral regurgitation after ring annuloplasty. PATIENTS AND METHODS: 40 consecutive patients (mean age, 70±8 years) with chronic ischemic mitral regurgitation grade ≥2+ received annuloplasty with an IMR ETlogix ring. During follow-up (25.9±15.5 months), 84% of surviving patients underwent exercise stress echocardiography to assess recurrence of mitral regurgitation and differences between rest and exercise mitral valve hemodynamic performance. RESULTS: Hospital mortality was 10%. During follow-up, we found no significant differences between left ventricular ejection fraction or end-diastolic and end-systolic diameters pre- and postoperatively (41% vs. 45%, 59 vs. 56 mm, and 49 vs. 46 mm, respectively), but there was a significant increase in mitral mean gradient with exercise (3.3±1.2 vs. 7.8±4 mmHg, p<0.001). Two patients had mitral regurgitation ≥grade III-IV. CONCLUSIONS: Mitral annuloplasty with the IMR ETlogix ring provides effective correction of chronic ischemic mitral regurgitation, but this technique may induce functional mitral stenosis.
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Martín et al. (2012) conducted an observational in chronic ischemic mitral regurgitation (n=40). Annuloplasty with an IMR ETlogix ring vs. Rest (pre-exercise) was evaluated on Mitral mean gradient with exercise vs rest (p=<0.001). Annuloplasty with the IMR ETlogix ring for ischemic mitral regurgitation significantly increased mitral mean gradient during exercise compared to rest (7.8 vs 3.3 mmHg, p<0.001).
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