Improved selectivity and decreased formation of overoxygenated byproducts were achieved by using a MeCN/H2O biphasic system for the iron-catalyzed oxidation of benzene to phenol with H2O2. Under optimized reaction conditions with 5-carboxy-2-methylpyrazine-N-oxide as the ligand for iron [Eq. (1)] a benzene conversion of 8.6 % and selectivities based on benzene and H2O2 of 97 and 88 %, respectively, were obtained.
No takes yet. Share an insight, caveat, or question.
Bianchi et al. (2000) studied this question.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: