Why the study?
Are endothelial cell and platelet function markers elevated in patients with Marfan's syndrome compared to matched controls?
Are endothelial cell and platelet function markers elevated in patients with Marfan's syndrome compared to matched controls?
Patients with Marfan's syndrome exhibit elevated markers of endothelial injury, which may be secondary to the impaired tensile strength of their blood vessels.
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Elevated endothelial markers may signal vascular injury in Marfan syndrome; hypothesis-generating and requires prospective validation before clinical implications.
Bridges et al. (1993) studied this question.
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