Key result
Motivational interviewing significantly reduced systolic blood pressure (MD -3.26) and diastolic blood pressure (MD -1.78) in patients with hypertension compared to standard care.
Why the study?
Improving medication compliance and self-efficacy is important for prognosis in hypertensive patients, but the role of motivational interviewing across blood pressure and patient-reported outcomes needed evaluation.
Does motivational interviewing reduce blood pressure and improve medication adherence in adults with hypertension?
Meta-Analysis
Does motivational interviewing reduce blood pressure and improve medication adherence in adults with hypertension?
Mean Difference: -3.26 (95% CI -5.16–-1.36)
p-value: p=<0.001
Motivational interviewing effectively reduces systolic and diastolic blood pressure in the short term while enhancing self-efficacy, quality of life, and medication adherence in hypertensive patients.
Motivational interviewing aids BP control and adherence in hypertension; reinforces behavioral interventions in guidelines and trials.
Background Improving medication compliance and self-efficacy in hypertensive patients is of significant importance for their prognosis. This meta-analysis aimed to assess the role of motivational interviewing in reducing systolic and diastolic blood pressure, self-efficacy, quality of life and medication adherence in hypertensive patients. Methods Two authors searched PubMed, Cochrane Library, Clinicaltrials, Embase, Web of Science, China National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database, Weipu and Wanfang Database up to May 28, 2024 for randomized controlled trials (RCTs) evaluating the role of motivational interviewing on hypertensive patients. The search was restricted to articles published in English and Chinese languages. RevMan 5.4 software was used for meta-analysis. Results A total of 16 RCTs were included. The meta-analysis findings demonstrate that motivational interviewing could reduce both systolic pressure [MD = −3.26, 95% CI (−5.16, −1.36), P < 0.001] and diastolic blood pressure [MD = −1.78, 95% CI (−3.48, −0.08), P < 0.001] levels in hypertensive patients, while simultaneously enhancing their self-efficacy [MD = 2.92, 95% CI (1.84, 4.00), P = 0.001], quality of life [MD = 6.99, 95% CI (3.25, 10.74), P = 0.003], and medication compliance [OR = 4.30, 95% CI (1.53, 12.10), P = 0.003]. No significant publication bias across the synthesized outcomes were found by Egger regression analyses (all P > 0.05). Conclusions Motivational interviewing has been shown to effectively reduce blood pressure in the short term among individuals with hypertension, while simultaneously enhancing their self-efficacy, quality of life, and adherence to medication regimens.
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Xu et al. (2025) conducted a meta-analysis in Hypertension. Motivational interviewing vs. Standard care was evaluated on Systolic blood pressure (MD -3.26, 95% CI -5.16, -1.36, p=<0.001). Motivational interviewing significantly reduced systolic blood pressure (MD -3.26) and diastolic blood pressure (MD -1.78) in patients with hypertension compared to standard care.
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