Key result
The novel CORE score demonstrated higher predictive accuracy for one-year COPD readmission than previous-year hospitalization (AUC 0.703 vs 0.619; P<0.001).
Why the study?
Previous prediction models for severe COPD exacerbations leading to readmission lacked newly established predictors such as the eosinophil count.
Does the CORE score accurately predict one-year COPD readmissions in patients with COPD?
Population
Patients visiting Taipei Tzu Chi Hospital between January 1, 2014, and May 31, 2017
Comparison
CORE score vs hospitalization in the previous year
Design
Retrospective medical record review
Follow-up
1 year
Authors
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May support CORE score for COPD readmission stratification; hypothesis-generating and requires prospective validation before practice change.
Cohort
No
Does the CORE score accurately predict one-year COPD readmissions in patients with COPD?
Hazard Ratio: 4.51
p-value: p=<0.001
The CORE score, which includes eosinophil count and triple inhaler therapy, provides high predictive accuracy for one-year COPD readmissions.
Wu et al. (2020) conducted a cohort in Chronic obstructive pulmonary disease (COPD). CORE score vs. Hospitalization in the previous year / Zero point reference was evaluated on One-year COPD readmission (HR 4.510, p=<0.001). The novel CORE score demonstrated higher predictive accuracy for one-year COPD readmission than previous-year hospitalization (AUC 0.703 vs 0.619; P<0.001).