The behavior of targeted quantum dots (Qdots) across three different tumor models using intravital microscopy with submicrometer resolution is described. As in the figure, the differences in extravasation between tumor types are shown and the kinetics are quatnified. Further, by demonstrating similarity in Qdot binding to tumor blood vessels across different tumor types, this work suggests several advantages implicit in vascular targeting compared with tumor cell targeting.
No takes yet. Share an insight, caveat, or question.
Smith et al. (2010) studied this question.