Population
Baby hamster kidney (BHK) cells and CS-54 arterial smooth muscle cells
Comparison
NO-releasing agent Deta-NONOate and transfection… vs Absence of Deta-NONOate, empty vector…
Design
Preclinical
Authors
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NO-cGMP-G kinase signaling regulates fos transcription in vitro; hypothesis-generating for cardiovascular gene expression in vivo.
This study demonstrates that nitric oxide regulates gene transcription via a soluble guanylate cyclase and type I cGMP-dependent protein kinase pathway.
Idriss et al. (1999) studied this question.
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