Lack of Nationwide Surveillance of Antimicrobial Resistance of Neisseria gonorrhoeae in Japan

Letters2 September 2008Lack of Nationwide Surveillance of Antimicrobial Resistance of Neisseria gonorrhoeae in JapanTakashi Deguchi, MD, Mitsuru Yasuda, MD, and Shin-ichi Maeda, MDTakashi Deguchi, MDFrom Gifu University, Gifu 501-1194, and Toyota Memorial Hospital, Toyota 471-8513, Japan.Search for more papers by this author, Mitsuru Yasuda, MDFrom Gifu University, Gifu 501-1194, and Toyota Memorial Hospital, Toyota 471-8513, Japan.Search for more papers by this author, and Shin-ichi Maeda, MDFrom Gifu University, Gifu 501-1194, and Toyota Memorial Hospital, Toyota 471-8513, Japan.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-149-5-200809020-00025 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail TO THE EDITOR:Workowski and colleagues (1) report the emerging antimicrobial resistance in Neisseria gonorrhoeae and the urgent need for an integrated, comprehensive approach to gonorrhea control. In particular, we agree with the importance of enhancement of national and international surveillance systems to monitor antimicrobial resistance. The Japanese government has not conducted nationwide surveillance of antimicrobial resistance of N. gonorrhoeae or placed high priority on funding such surveillance. Antimicrobial resistance of N. gonorrhoeae has not been controlled in an efficient or timely manner to prolong the efficacy of existing antibiotics. As a consequence, effective oral regimens for treatment of gonorrhea ...References1. Workowski KA, Berman SM, Douglas JM. Emerging antimicrobial resistance in Neisseria gonorrhoeae: urgent need to strengthen prevention strategies. Ann Intern Med. 2008;148:606-13. [PMID: 18413622] LinkGoogle Scholar2. Ito M, Yasuda M, Yokoi S, Ito S, Takahashi Y, Ishihara S, et al. Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones. Antimicrob Agents Chemother. 2004;48:3185-7. [PMID: 15273147] CrossrefMedlineGoogle Scholar3. Ito M, Deguchi T, Mizutani KS, Yasuda M, Yokoi S, Ito S, et al. Emergence and spread of Neisseria gonorrhoeae clinical isolates harboring mosaic-like structure of penicillin-binding protein 2 in Central Japan. Antimicrob Agents Chemother. 2005;49:137-43. [PMID: 15616287] CrossrefMedlineGoogle Scholar4. Yasuda M, Hagiwara N, Ishihara S, Maeda S, Deguchi T. Remarkable increase of Neisseria gonorrhoeae with decreased susceptibility to cefixime and azithromycin. [Abstract]. Presented at the 46th Interscience Conference on Antimicrobial Agents and Chemotherapy, San Francisco, California; 27-30 September, 2006: Abstract L2-1230. Google Scholar Author, Article, and Disclosure InformationAffiliations: From Gifu University, Gifu 501-1194, and Toyota Memorial Hospital, Toyota 471-8513, Japan.Disclosures: None disclosed. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetailsSee AlsoEmerging Antimicrobial Resistance in Neisseria gonorrhoeae: Urgent Need to Strengthen Prevention Strategies Kimberly A. Workowski , Stuart M. Berman , and John M. 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