Phosgene as a Reagent for the Enantiomeric Resolution of 1,2‐ and 1,3‐Diols, α‐Amino Alcohols, α‐Hydroxy Acids, and N‐Methyl‐α‐Amino Acids by Gas Chromatography

The enantiomeric compositions of chiral diols can be determined by gas chromatography. 1,2- and 1,3-Diols, respectively, are converted by phosgene-containing solutions into 1 and 2, which are separated on the chiral stationary phase XE-60-L-valine-(R)-α-phenylethylamide. Additional classes of compounds which can also be resolved analogously are mentioned in the title.