Key result
Ultra-troponin I testing in the first 3 hours of chest pain onset showed 74% sensitivity and 68% specificity for detecting coronary artery disease, with sensitivity improving to 90% upon serial measurements.
Why the study?
Does serial measurement of ultra-troponin I improve the diagnostic accuracy for acute coronary syndrome in patients presenting with chest pain?
Observational (n=200)
No
Does serial measurement of ultra-troponin I improve the diagnostic accuracy for acute coronary syndrome in patients presenting with chest pain?
Serial measurements of ultra-troponin I significantly improve diagnostic sensitivity and predictive values for acute coronary syndrome compared to a single baseline measurement.
Serial ultra-troponin I may aid early ACS evaluation; hypothesis-generating and requires prospective validation before practice change.
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Doğan et al. (2015) conducted an observational in Chest pain / Suspected acute coronary syndrome (n=200). Ultra-Troponin I testing was evaluated on Diagnostic performance (sensitivity and specificity) of Ultra-TnI for detecting coronary artery disease. Ultra-troponin I testing in the first 3 hours of chest pain onset showed 74% sensitivity and 68% specificity for detecting coronary artery disease, with sensitivity improving to 90% upon serial measurements.
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