Why the study?
What is the diagnostic accuracy of early S-myoglobin measurement for acute myocardial infarction?
Population
291 patients suspected for acute myocardial infarction, with an AMI prevalence of 0.45 and a male to female…
Design
Cross-sectional
Authors
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May support early AMI rule-out in select settings; leaves open incremental value over modern troponin assays.
What is the diagnostic accuracy of early S-myoglobin measurement for acute myocardial infarction?
Early measurement of S-myoglobin has high sensitivity but lower specificity for diagnosing acute myocardial infarction, with diagnostic performance heavily dependent on the chosen discrimination limit and disease prevalence.
Nørregaard-Hansen et al. (1986) studied this question.
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