Why the study?
What is the time course and specificity of serum myoglobin and muscle enzymes in patients with myocardial infarction and cardiac arrhythmias?
Population
15 patients (9 with a final diagnosis of myocardial infarction, 6 with cardiac arrhythmias)
Design
Cohort
Follow-up
first few days of hospitalization
Authors
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Myoglobin and CK-2 may aid early MI detection while cardioversion confounds total CK; leaves open validation in larger prospective cohorts.
What is the time course and specificity of serum myoglobin and muscle enzymes in patients with myocardial infarction and cardiac arrhythmias?
Myoglobin and CK-2 provide early detection of myocardial infarction, while cardioversion can elevate myoglobin and total CK without affecting CK-2 or LDH-1.
Rosano et al. (1977) studied this question.