Why the study?
Do gonadotropins and pregnancy affect prorenin and renin levels in adult female rats?
Do gonadotropins and pregnancy affect prorenin and renin levels in adult female rats?
Gonadotropins and pregnancy affect the renin-angiotensin system in rats, but the small magnitude of plasma changes does not support a systemic role of prorenin for reproduction in this species.
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Rat responses to gonadotropins differ markedly from humans; leaves open prorenin’s systemic role in reproduction.
Nielsen et al. (1991) studied this question.
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