Key result
Snoring was significantly associated with elevated triglyceride levels compared to non-snoring, with a pooled standardized mean difference of 0.23.
Why the study?
High TG levels are important risk factors for CVD and recent studies have linked snoring to elevated TG, but the specific pathogenesis remains unclear.
Does snoring increase triglyceride levels in adults?
Meta-Analysis (n=39,102)
Does snoring increase triglyceride levels in adults?
Standardized Mean Difference: 0.23 (95% CI 0.14–0.32)
p-value: p=<0.00001
Occasional and habitual snoring are significantly associated with elevated triglyceride levels, independent of body mass index.
Snoring-associated TG elevation may prompt sleep assessment in CVD risk evaluation; leaves open causality and whether interventions alter lipids or outcomes.
High triglyceride (TG) levels are important risk factors for cardiovascular disease (CVD). Some recent studies have shown that snoring is also closely related to elevated TG levels. The specific pathogenesis of elevated TG levels in snoring patients is still unclear. Therefore, we performed this meta-analysis to evaluate the relationship between snoring and elevated TG levels. A systematic search was conducted in four online electronic databases as of Jul 1, 2024. The standardized mean difference (SMD) and corresponding 95% confidence interval (CI) for TG levels in each study were pooled. Moreover, we performed subgroup analysis according to snoring status and body mass index (BMI). All the data were pooled and analysed with Review Manager 5.3. The meta-analysis included five studies with 39,102 participants. Our results revealed that snoring was associated with elevated TG levels, with a pooled SMD of 0.23 (95% CI 0.14 to0.32; P < 0.00001). We found that occasional snoring and habitual snoring were associated with high TG levels, with pooled SMD of 0.26 (95% CI 0.04to0.49; P = 0.002) and 0.29 (95% CI 0.16to0.43; P < 0.0001), respectively. According to the subgroup analysis of BMI, BMI < 25 kg/m 2 and BMI ≥ 25 kg/m 2 were associated with increased TG levels, with pooled SMD of 0.13 (95% CI 0.04 to 0.22; P = 0.004) and 0.24 (95% CI 0.10 to 0.39; P = 0.0007), respectively. Our meta-analysis revealed that both occasional and habitual snoring were associated with elevated TG levels. More importantly, our findings also revealed that the relationship between snoring-induced elevated TG levels and BMI was fragile.
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Hou et al. (2024) conducted a meta-analysis in Snoring and elevated triglyceride levels (n=39,102). Snoring vs. Non-snoring was evaluated on Triglyceride levels (SMD 0.23, 95% CI 0.14 to 0.32, p=<0.00001). Snoring was significantly associated with elevated triglyceride levels compared to non-snoring, with a pooled standardized mean difference of 0.23.
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