Key result
Each unit increase in the Framingham Steatosis Index was associated with a 36% higher odds of obstructive sleep apnea (OR 1.36).
Why the study?
Given the robust correlation between MAFLD and OSA, the correlation between FSI and OSA, along with potential mediating mechanisms, remained unclear.
Does a higher Framingham Steatosis Index correlate with an increased risk of obstructive sleep apnea in US adults?
Cross-Sectional (n=8,945)
Does a higher Framingham Steatosis Index correlate with an increased risk of obstructive sleep apnea in US adults?
Odds Ratio: 1.36 (95% CI 1.31–1.42)
p-value: p=<0.01
The Framingham Steatosis Index is positively and non-linearly associated with the risk of obstructive sleep apnea, suggesting its potential utility as a screening indicator for OSA risk.
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Ma et al. (2025) conducted a cross-sectional in Obstructive sleep apnea (n=8,945). Framingham Steatosis Index (FSI) vs. Lower FSI values was evaluated on Obstructive sleep apnea (OSA) (OR 1.36, 95% CI 1.31-1.42, p=<0.01). Each unit increase in the Framingham Steatosis Index was associated with a 36% higher odds of obstructive sleep apnea (OR 1.36).
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