Skin perfusion pressure measured by radioisotope washout for predicting wound healing in lower limb amputation for arterial occlusive disease

This dissertation is based on the following papers, to be referred to in the text by Roman numerals.I. Holstein, P., Lund, P., Larsen, B. & Schoemacker, T. (1977).Skin perfusion pressure measured as the external pressure required to stop isotope washout.Methodological considerations and normal values on the legs.Scand.J. clin.Lab.Invest.37,649-659.11.Bolund, S. & Holstein, P. (1976).Blood flow cessation at external pressure in rat skin flaps.Isotope washout compared to vital capillary microscopy.Microvasc.Res.11, 381-390.111.Holstein, P., Nielsen, P. E. & Barras, J.-P. (1979).Blood flow cessation at external pressure in the skin of normal human limbs.Photoelectric recordings compared to isotope washout and to local intra-arterial blood pressure.Microvasc.